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Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5)

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ACS2; ACS5; FACL5; Long-Chain Fatty Acid Coenzyme A Ligase 5

Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5)
CCC D675
HGNC 16526
MGI 1919129
PubMed 24770931
RGD 69402
UniProt Q9ULC5
Wiki ACSL5
Long-chain-fatty-acid--CoA ligase 5 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.
This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD675Hu01 Recombinant Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD675Mu01 Recombinant Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Acyl Coenzyme A Synthetase Long Chain Family, Member 5 (ACSL5) ELISA Kit Customized Service Offer
  1. "Regulation of enterocyte apoptosis by acyl-CoA synthetase 5 splicing."Gastroenterology 133:587-598(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide."Cancer Sci. 100:1556-1562(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions."Oncogene 28:9-19(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]