Lipolysis Stimulated Lipoprotein Receptor (LSR)
[Edit]LISCH7; ILDR3; LISCH; Lipolysis-Stimulated Remnant; Immunoglobulin-Like Domain Containing Receptor 3
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LSR is a multimeric protein complex in the liver that undergoes conformational changes upon binding of free fatty acids, thereby revealing a binding site (s) that recognizes both apoB and apoE. Complete inactivation of the LSR gene is embryonic lethal in mice.LSR cooperates with the LDL receptor in the final hepatic processing of apoB-containing lipoproteins and represents a novel therapeutic target for the treatment of hyperlipidemia associated with obesity and atherosclerosis. The lipolysis-stimulated receptor (LSR) is a lipoprotein receptor primarily expressed in the liver and activated by free fatty acids. Antibodies inhibiting LSR functions showed that the receptor is a heterotrimer or tetramer consisting of 68-kDa (alpha) and 56-kDa (beta) subunits associated through disulfide bridges.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD744Mu01 | Recombinant Lipolysis Stimulated Lipoprotein Receptor (LSR) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPD744Mu02 | Recombinant Lipolysis Stimulated Lipoprotein Receptor (LSR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAD744Mu01 | Polyclonal Antibody to Lipolysis Stimulated Lipoprotein Receptor (LSR) | WB; ICC/IF |
PAD744Mu02 | Polyclonal Antibody to Lipolysis Stimulated Lipoprotein Receptor (LSR) | WB; IHC; ICC; IP. | |
Assay Kits | SED744Mu | ELISA Kit for Lipolysis Stimulated Lipoprotein Receptor (LSR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Lipolysis Stimulated Lipoprotein Receptor (LSR) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Lipolysis Stimulated Lipoprotein Receptor (LSR) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Lipolysis Stimulated Lipoprotein Receptor (LSR) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Lipolysis Stimulated Lipoprotein Receptor (LSR) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Lipolysis Stimulated Lipoprotein Receptor (LSR) | ELISA Kit Customized Service Offer |
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