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Small Proline Rich Protein 2A (SPRR2A)

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Small Proline Rich Protein 2A (SPRR2A)
CCC D804
HGNC 11261
MGI 1330344
PubMed 22731250
UniProt P35326
Wiki SPRR2A
SPRR genes encode a novel class of polypeptides called small proline-rich proteins that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. Small proline-rich protein 2A is a protein encoded by the SPRR2A gene.Gibbs et al. (1993) concluded that there are 7 genes for the SPRR2 subfamily of small proline-rich proteins, including SPRR2A.Using DNA microarray analysis, Zimmermann et al. (2005) identified Sprr2a and Sprr2b (182268) as allergen-induced genes in a mouse model of experimental asthma.
By analysis of human-rodent hybrid cell lines and FISH, Gibbs et al. (1993) determined that all SPRR genes, including SPRR2A, are closely linked within a 300-kb DNA segment on chromosome 1q21-q22.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD804Hu01 Recombinant Small Proline Rich Protein 2A (SPRR2A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD804Hu01 Polyclonal Antibody to Small Proline Rich Protein 2A (SPRR2A) WB; IHC; ICC; IP.
Assay Kits SED804Hu ELISA Kit for Small Proline Rich Protein 2A (SPRR2A) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD804Mu01 Recombinant Small Proline Rich Protein 2A (SPRR2A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Small Proline Rich Protein 2A (SPRR2A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Small Proline Rich Protein 2A (SPRR2A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Small Proline Rich Protein 2A (SPRR2A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Proline Rich Protein 2A (SPRR2A) ELISA Kit Customized Service Offer
  1. "Characterization of the human spr2 promoter: induction after UV irradiation or TPA treatment and regulation during differentiation of cultured primary keratinocytes."Nucleic Acids Res. 18:4401-4407(1990) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins."Genomics 16:630-637(1993) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]