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Small Proline Rich Protein 3 (SPRR3)

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SPRC; Esophagin; Cornifin beta; 22 kDa pancornulin

Small Proline Rich Protein 3 (SPRR3)
CCC D805
HGNC 11268
MGI 1330237
PubMed 22076481
RGD 1309589
UniProt Q9UBC9
Wiki SPRR3
Gibbs et al. (1993) showed that the SPRR proteins are encoded by closely related members of a gene family, consisting of 2 genes for SPRR1 (SPRR1A and SPRR1B), approximately 7 genes for SPRR2, and a single gene for SPRR3. All SPRR genes are closely linked within a 300-kb DNA segment on 1q21-q22, a region where the related loricrin and involucrin genes have also been mapped. By pulsed-field gel electrophoresis analysis, Gibbs et al. (1993) concluded that the SPRR1 genes are located between the SPRR2 genes and the SPRR3 gene.
Gibbs et al. (1993) concluded that there is a single gene for the SPRR3 subfamily of small proline-rich proteins. All SPRR genes are closely linked within a 300-kb DNA segment on 1q21-q22.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD805Hu01 Recombinant Small Proline Rich Protein 3 (SPRR3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD805Hu01 Polyclonal Antibody to Small Proline Rich Protein 3 (SPRR3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Small Proline Rich Protein 3 (SPRR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Proline Rich Protein 3 (SPRR3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Small Proline Rich Protein 3 (SPRR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Small Proline Rich Protein 3 (SPRR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Small Proline Rich Protein 3 (SPRR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Small Proline Rich Protein 3 (SPRR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Proline Rich Protein 3 (SPRR3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Small Proline Rich Protein 3 (SPRR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Small Proline Rich Protein 3 (SPRR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Small Proline Rich Protein 3 (SPRR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Small Proline Rich Protein 3 (SPRR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Proline Rich Protein 3 (SPRR3) ELISA Kit Customized Service Offer
  1. "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins."Genomics 16:630-637(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Differential expression of protease inhibitor and small proline-rich protein genes between normal human oral tissue and odontogenic keratocysts."Arch. Oral Biol. 39:251-259(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Esophagin cDNA cloning and characterization: a tissue-specific member of the small proline-rich protein family that is not expressed in esophageal tumors."Cell Growth Differ. 7:855-860(1996) [PubMed] [Europe PMC] [Abstract]
  4. "Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library."Genome Res. 11:341-355(2001) [PubMed] [Europe PMC] [Abstract]
  5. "Characterization of two isoforms of human SPRR3 from saliva of preterm human newborn and autoptic fetal oral mucosa, parotid and submandibular gland samples."Biochem. Biophys. Res. Commun. 398:477-481(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  8. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  10. "The pancornulins: a group of small proline rich-related cornified envelope precursors with bifunctional capabilities in isopeptide bond formation."J. Invest. Dermatol. 104:204-210(1995) [PubMed] [Europe PMC] [Abstract]