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Phosphoserine Aminotransferase 1 (PSAT1)

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PSA; EPIP; Endometrial Progesterone Induced Protein; Phosphohydroxythreonine aminotransferase

Phosphoserine Aminotransferase 1 (PSAT1)
CCC D861
HGNC 19129
MGI 2183441
PubMed 18221502
RGD 735170
UniProt Q9Y617
Wiki PSAT1
PSAT catalyzes the second step in the pathway, conversion of 3-phosphohydroxypyruvate into 3-phosphoserine. The full-length PSAT-beta transcript encodes a deduced 370-amino acid protein with a calculated molecular mass of 40 kD. PSAT-alpha lacks exon 8 and encodes a deduced 324-amino acid protein with a calculated molecular mass of 35.2 kD. Compared with PSAT-beta, PSAT-alpha lacks 46 amino acids. Both proteins contain a conserved binding domain for the cofactor pyridoxal 5-prime-phosphate (vitamin B6). PSAT-beta shares 92.4% amino acid similarity with its mouse homolog. PSAT-beta orthologs were present in all species examined, including plants, insects, and bacteria.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD861Hu01 Recombinant Phosphoserine Aminotransferase 1 (PSAT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD861Hu01 Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) WB,IHC,ICC/IF
MAD861Hu21 Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) WB; IHC; ICC; IP.
Assay Kits SCD861Hu CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) Chemiluminescent immunoassay for Antigen Detection.
SED861Hu ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphoserine Aminotransferase 1 (PSAT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphoserine Aminotransferase 1 (PSAT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) ELISA Kit Customized Service Offer
  1. "Characterization of human phosphoserine aminotransferase involved in the phosphorylated pathway of L-serine biosynthesis."Biochem. J. 373:191-200(2003) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Phosphoserine aminotransferase deficiency: a novel disorder of the serine biosynthesis pathway."Am. J. Hum. Genet. 80:931-937(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "Neu-Laxova syndrome is a heterogeneous metabolic disorder caused by defects in enzymes of the L-serine biosynthesis pathway." Am. J. Hum. Genet. 95:285-293(2014) [PubMed] [Europe PMC] [Abstract]