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Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19)

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TAJ; TAJ-alpha; TRADE; TROY; Toxicity And JNK Inducer

Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19)
CCC D928
HGNC 11915
MGI 1352474
PubMed 24623448
UniProt Q9NS68
Wiki TNFRSF19
Tumor necrosis factor receptor superfamily, member 19 is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells.
This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD928Hu01 Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD928Hu01 Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD928Mu01 Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD928Mu01 Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19) ELISA Kit Customized Service Offer
  1. "TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death."J. Biol. Chem. 275:15336-15342(2000) [PubMed] [Europe PMC] [Abstract]
  2. "TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles."J. Biol. Chem. 275:20742-20747(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  8. "A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors."Neuron 45:345-351(2005) [PubMed] [Europe PMC] [Abstract]