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Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2)

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ARP1; COUP-TFII; COUPTFB; SVP40; TFCOUP2; Apolipoprotein A-I regulatory protein 1

Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2)
CCC D958
HGNC 7976
MGI 1352452
RGD 69305
UniProt P24468
Chicken ovalbumin upstream promoter transcription factors (COUP-TFs) are members of the steroid/thyroid hormone receptor superfamily. The protein sequences are highly homologous across species, suggesting functional conservation. ARP1, also called COUP-TFII, and COUP-TFI were cloned from the human, and their genomic organization characterized.
COUP-TFII plays a critical role in controlling the development of a number of tissues and organs including heart, blood vessels, muscles and limbs.The glucocorticoid receptor (GR) stimulates COUP-TFII-induced transactivation while COUP-TFII represses the GR transcriptional activity. COUP-TFII interacts with GATA2 to inhibit adipocyte differentiation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2) ELISA Kit Customized Service Offer
  1. "Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily."Science 251:561-565(1991) [PubMed] [Europe PMC] [Abstract]
  2. "DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system."FEBS Lett. 582:2737-2744(2008) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The COUP-TFs compose a family of functionally related transcription factors."Gene Expr. 1:207-216(1991) [PubMed] [Europe PMC] [Abstract]
  7. "The nuclear orphan receptors COUP-TFII and Ear-2 act as silencers of the human oxytocin gene promoter."J. Mol. Endocrinol. 19:163-172(1997) [PubMed] [Europe PMC] [Abstract]
  8. "Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2."J. Biol. Chem. 274:14331-14336(1999) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor."PLoS Biol. 6:E227-E227(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Rare variants in NR2F2 cause congenital heart defects in humans." Am. J. Hum. Genet. 94:574-585(2014) [PubMed] [Europe PMC] [Abstract]