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Protocadherin Alpha 8 (PCDHa8)

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Protocadherin Alpha 8 (PCDHa8)
CCC E088
HGNC 8674
PubMed 21962230
UniProt Q9Y5H6
PCDHA8 is 1 of 15 tandemly arranged genes within the PCDHA gene cluster on chromosome 5q31. The 15 PCDHA genes function as 'variable' exons that are individually spliced to a downstream constant region to form distinct PCDHA transcripts. By genomic sequence analysis, Wu et al. (2001) mapped the PCDHA8 gene to chromosome 5q31. They localized the mouse PCDHA genes to chromosome 18c.
Noonan et al. (2003) identified a 16.7-kb deletion within the PCDHA gene cluster that truncated the PCDHA8 gene and completely removed the PCDHA9 and PCDHA10 genes. This deletion appeared in 'normal' individuals from multiple populations, suggesting that a reduction in protocadherin gene number is not obviously deleterious.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protocadherin Alpha 8 (PCDHa8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protocadherin Alpha 8 (PCDHa8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protocadherin Alpha 8 (PCDHa8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protocadherin Alpha 8 (PCDHa8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protocadherin Alpha 8 (PCDHa8) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE088Ra01 Recombinant Protocadherin Alpha 8 (PCDHa8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Protocadherin Alpha 8 (PCDHa8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protocadherin Alpha 8 (PCDHa8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protocadherin Alpha 8 (PCDHa8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protocadherin Alpha 8 (PCDHa8) ELISA Kit Customized Service Offer
  1. "A striking organization of a large family of human neural cadherin-like cell adhesion genes."Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]