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PCDHA10 is 1 of 15 tandemly arranged genes within the PCDHA gene cluster on chromosome 5q31. The 15 PCDHA genes function as 'variable' exons that are individually spliced to a downstream constant region to form distinct PCDHA transcripts. These transcripts encode cadherin-like cell surface proteins that are expressed in neurons and are present at synaptic junctions.
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Noonan et al. (2003) identified a 16.7-kb deletion within the PCDHA gene cluster that truncated the PCDHA8 gene and completely removed the PCDHA9 and PCDHA10 genes. This deletion appeared in 'normal' individuals from multiple populations, suggesting that a reduction in protocadherin gene number is not obviously deleterious
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE090Hu01 | Recombinant Protocadherin Alpha 10 (PCDHa10) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Protocadherin Alpha 10 (PCDHa10) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Protocadherin Alpha 10 (PCDHa10) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Protocadherin Alpha 10 (PCDHa10) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Protocadherin Alpha 10 (PCDHa10) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Protocadherin Alpha 10 (PCDHa10) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Protocadherin Alpha 10 (PCDHa10) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Protocadherin Alpha 10 (PCDHa10) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Protocadherin Alpha 10 (PCDHa10) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Protocadherin Alpha 10 (PCDHa10) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Protocadherin Alpha 10 (PCDHa10) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Protocadherin Alpha 10 (PCDHa10) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Protocadherin Alpha 10 (PCDHa10) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Protocadherin Alpha 10 (PCDHa10) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Protocadherin Alpha 10 (PCDHa10) | ELISA Kit Customized Service Offer |
- "A striking organization of a large family of human neural cadherin-like cell adhesion genes."Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]