Gamma-Glutamyltransferase 5 (gGT5)
[Edit]GGTLA1; GGT-REL; Gamma-Glutamyltransferase-Like Activity 1; Gamma-glutamyl transpeptidase-related enzyme; Leukotriene-C4 hydrolase; Glutathione hydrolase 5
Gamma-glutamyltransferase-like activity 1 (GGTLA1) is a member of a gene family that encodes gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn't convert synthetic substrates that are commonly used to assay gamma-glutamyl transpeptidase.
GGT5 belongs to the gamma-glutamyltransferase (GGT) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE140Hu01 | Recombinant Gamma-Glutamyltransferase 5 (gGT5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAE140Hu01 | Polyclonal Antibody to Gamma-Glutamyltransferase 5 (gGT5) | WB; IHC; ICC; IP. |
MAE140Hu21 | Monoclonal Antibody to Gamma-Glutamyltransferase 5 (gGT5) | WB; IHC; ICC; IP. | |
Assay Kits | SEE140Hu | ELISA Kit for Gamma-Glutamyltransferase 5 (gGT5) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Gamma-Glutamyltransferase 5 (gGT5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Gamma-Glutamyltransferase 5 (gGT5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Gamma-Glutamyltransferase 5 (gGT5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Gamma-Glutamyltransferase 5 (gGT5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Gamma-Glutamyltransferase 5 (gGT5) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Gamma-Glutamyltransferase 5 (gGT5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Gamma-Glutamyltransferase 5 (gGT5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Gamma-Glutamyltransferase 5 (gGT5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Gamma-Glutamyltransferase 5 (gGT5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Gamma-Glutamyltransferase 5 (gGT5) | ELISA Kit Customized Service Offer |
- "Identification of a human gamma-glutamyl cleaving enzyme related to, but distinct from, gamma-glutamyl transpeptidase."Proc. Natl. Acad. Sci. U.S.A. 88:6303-6307(1991) [PubMed] [Europe PMC] [Abstract]
- "A genome annotation-driven approach to cloning the human ORFeome."Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of human chromosome 22." Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]