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Adenosine Deaminase, tRNA Specific 2 (ADAT2)

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TAD2; DEADC1; Deaminase Domain Containing 1; tRNA-specific adenosine-34 deaminase subunit ADAT2

Adenosine Deaminase, tRNA Specific 2 (ADAT2)
CCC E156
HGNC 21172
MGI 1914007
PubMed 16142903
UniProt Q7Z6V5
ADAT2 is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts.
The mammalian RNA-specific adenosine deaminases (ADARs) constitute a family of sequence-related proteins involved in pre-mRNA editing of nuclear transcripts through site-specific adenosine modification. Maas et al. (1999) identified and characterized a human ADAR-related protein that specifically deaminates adenosine-37 to inosine in eukaryotic tRNA(ala). Adenosine deaminase (also known as ADA) is an enzyme (EC 3.5.4.4) involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Adenosine Deaminase, tRNA Specific 2 (ADAT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Adenosine Deaminase, tRNA Specific 2 (ADAT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Adenosine Deaminase, tRNA Specific 2 (ADAT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Adenosine Deaminase, tRNA Specific 2 (ADAT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Adenosine Deaminase, tRNA Specific 2 (ADAT2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Adenosine Deaminase, tRNA Specific 2 (ADAT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Adenosine Deaminase, tRNA Specific 2 (ADAT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Adenosine Deaminase, tRNA Specific 2 (ADAT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Adenosine Deaminase, tRNA Specific 2 (ADAT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Adenosine Deaminase, tRNA Specific 2 (ADAT2) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "RNA editing by adenosine deaminases generates RNA and protein diversity."Biochimie 84:791-803(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Crystal structure of human tRNA-specific adenosine-34 deaminase subunit ADAT2."Submitted (FEB-2009) to the PDB data bank