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Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2)

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PAFAHB; PAF acetylhydrolase 30 kDa subunit; PAF-AH subunit beta; Platelet-activating factor acetylhydrolase IB subunit beta

Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2)
CCC E159
HGNC 8575
MGI 108415
PubMed 17849047
RGD 620332
UniProt P68402
Wiki PAFAH1B2
Platelet-activating factor (PAF) is a biologically active phospholipid with diverse biologic effects. PAF is degraded to inactive products by hydrolysis of the acetyl group at the sn-2 position to produce the biologically inactive products LYSO-PAF and acetate. This reaction is catalyzed by PAF acetylhydrolase (PAFAH). The various monomeric and multimeric forms of the enzyme are composed of alpha , beta, and gamma PAFAH subunits.
The PAFAH1B2 gene encodes a 229-amino acid polypeptide with a molecular mass of 30 kD. The human PAFAH1B2 amino acid sequence is 62.4% identical to that of the human gamma subunit. Northern blot analysis revealed that the gene was expressed as a 4.0-kb mRNA in all human adult and fetal tissues tested.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Platelet Activating Factor Acetylhydrolase Ib2 (PAFAH1B2) ELISA Kit Customized Service Offer
  1. "Differential tissue distribution of the beta- and gamma-subunits of human cytosolic platelet-activating factor acetylhydrolase (isoform I)."Biochem. Biophys. Res. Commun. 233:10-13(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Novel isoforms of intracellular platelet activating factor acetylhydrolase (PAFAH1b2) in human testis; encoded by alternatively spliced mRNAs."Prostaglandins Other Lipid Mediat. 85:69-80(2008) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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  6. , Submitted (MAR-2007) to UniProtKB
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]