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Vasoactive Intestinal Peptide Receptor 2 (VIPR2)

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VPAC2; VIP2R; Helodermin-preferring VIP receptor; Pituitary adenylate cyclase-activating polypeptide type III receptor

Vasoactive Intestinal Peptide Receptor 2 (VIPR2)
CCC E163
HGNC 12695
MGI 107166
PubMed 21346763
RGD 3962
UniProt P41587
Wiki VIPR2
Vasoactive intestinal peptide receptor 2 is a G-protein coupled receptor encoded by the VIPR2 gene. It is expressed in humans in the uterus, prostate, smooth muscle of the gastrointestinal tract, seminal vesicles and skin, blood vessels and thymus. Research using VPAC2 knockout mice implicate it in the function of the circadian clock, growth, basal energy expenditure and male reproduction
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) are homologous peptides that function as neurotransmitters and neuroendocrine hormones. While the receptors for VIP and PACAP share homology, they differ in their substrate specificities and expression patterns.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vasoactive Intestinal Peptide Receptor 2 (VIPR2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vasoactive Intestinal Peptide Receptor 2 (VIPR2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vasoactive Intestinal Peptide Receptor 2 (VIPR2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vasoactive Intestinal Peptide Receptor 2 (VIPR2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vasoactive Intestinal Peptide Receptor 2 (VIPR2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vasoactive Intestinal Peptide Receptor 2 (VIPR2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vasoactive Intestinal Peptide Receptor 2 (VIPR2) ELISA Kit Customized Service Offer
  1. "Molecular cloning and functional characterization of a human VIP receptor from SUP-T1 lymphoblasts."Biochem. Biophys. Res. Commun. 205:1617-1624(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Chromosomal localization in mouse and human of the vasoactive intestinal peptide receptor type 2 gene: a possible contributor to the holoprosencephaly 3 phenotype."Genomics 37:345-353(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Tissue specific expression of different human receptor types for pituitary adenylate cyclase activating polypeptide and vasoactive intestinal polypeptide: implications for their role in human physiology."J. Neuroendocrinol. 8:811-817(1996) [PubMed] [Europe PMC] [Abstract]
  4. "Structure of the human VIP2R gene for vasoactive intestinal peptide type 2 receptor."FEBS Lett. 458:197-203(1999) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  9. "Predominant expression of type II vasoactive intestinal peptide receptors by human T lymphoblastoma cells: transduction of both Ca2+ and cyclic AMP signals."J. Clin. Immunol. 16:21-30(1996) [PubMed] [Europe PMC] [Abstract]
  10. "Crystal structure of the extracellular domain of human vasoactive intestinal polypeptide receptor 2."Submitted (MAR-2010) to the PDB data bank