Peptidylprolyl Isomerase G (PPIG)

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PPI-G; CARS-Cyp; CYP; SRCyp; CASP10; Peptidyl-Prolyl Isomerase G; Cyclophilin G; Peptidyl-prolyl cis-trans isomerase G; Clk-associating RS-cyclophilin; Rotamase G

Peptidylprolyl Isomerase G (PPIG)
PPIG is predicted to encode a 754-amino acid protein containing 2 Nopp140 (nucleolar phosphoprotein of 140 kD)-related domains and a large C-terminal serine/arginine (SR)-rich domain found predominantly in pre-mRNA splicing factors. The N-terminal region of PPIG contains a peptidyl-prolyl cis-trans isomerase domain characteristic of immunophilins/cyclophilins. PPIG shares 37.8% sequence identity with NKTR, a myeloid-specific nuclear protein. By Northern blot analysis, Nestel et al. (1996) detected PPIG expression at similar levels in lung, liver, kidney, small intestine, testis, and brain. They detected major 4-kb and minor 10-kb PPIG transcripts in human B-cell RNA. Although PPIG was widely expressed, it appeared to be absent from NK cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peptidylprolyl Isomerase G (PPIG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peptidylprolyl Isomerase G (PPIG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peptidylprolyl Isomerase G (PPIG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peptidylprolyl Isomerase G (PPIG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peptidylprolyl Isomerase G (PPIG) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peptidylprolyl Isomerase G (PPIG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peptidylprolyl Isomerase G (PPIG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peptidylprolyl Isomerase G (PPIG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peptidylprolyl Isomerase G (PPIG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peptidylprolyl Isomerase G (PPIG) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peptidylprolyl Isomerase G (PPIG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peptidylprolyl Isomerase G (PPIG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peptidylprolyl Isomerase G (PPIG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peptidylprolyl Isomerase G (PPIG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peptidylprolyl Isomerase G (PPIG) ELISA Kit Customized Service Offer
  1. "RS cyclophilins: identification of an NK-TR1-related cyclophilin."Gene 180:151-155(1996) [PubMed] [Europe PMC] [Abstract]
  2. "A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II."Nucleic Acids Res. 25:2055-2061(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Over-expression of SR-cyclophilin, an interaction partner of nuclear pinin, releases SR family splicing factors from nuclear speckles."Biochem. Biophys. Res. Commun. 321:638-647(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]