RAN Binding Protein 2 (RANBP2)
[Edit]p270; NUP358; E3 SUMO-protein ligase RanBP2; 358 kDa nucleoporin; Nuclear pore complex protein Nup358; Nucleoporin Nup358
RanBP2 is also known as Nup358 since it is a member nucleoporin family that makes-up the nuclear pore complex. RanBP2 has a 358 KDa molecular weight.The RanBP2 gene encodes a very large RAN-binding protein that localizes to cytoplasmic filaments emanating from the nuclear pore complex. RanBP2/Nup358 is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in controlling selective processes of the the Ran-GTPase cycle. RanBP2 is composed of multiple domains. Each domain of RanBP2 selectively and directly interacts with distinct proteins such as Ran GTPase, importin-beta, exportin-1/CRM1, red opsin, subunits of the proteasome, cox11 and the kinesin-1 isoforms, KIF5B and KIF5C. Another partner of RanBP2 is the E2 enzyme UBC9.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant RAN Binding Protein 2 (RANBP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to RAN Binding Protein 2 (RANBP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to RAN Binding Protein 2 (RANBP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for RAN Binding Protein 2 (RANBP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for RAN Binding Protein 2 (RANBP2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant RAN Binding Protein 2 (RANBP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to RAN Binding Protein 2 (RANBP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to RAN Binding Protein 2 (RANBP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for RAN Binding Protein 2 (RANBP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for RAN Binding Protein 2 (RANBP2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant RAN Binding Protein 2 (RANBP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to RAN Binding Protein 2 (RANBP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to RAN Binding Protein 2 (RANBP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for RAN Binding Protein 2 (RANBP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for RAN Binding Protein 2 (RANBP2) | ELISA Kit Customized Service Offer |
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- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
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- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
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- "Solution structure of the Ran-binding domain 2 of RanBP2 and its interaction with the C terminus of Ran."J. Mol. Biol. 348:711-725(2005) [PubMed] [Europe PMC] [Abstract]
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- "Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2."J. Biol. Chem. 287:4740-4751(2012) [PubMed] [Europe PMC] [Abstract]
- "Crystal structure of the N-terminal domain of Nup358/RanBP2."J. Mol. Biol. 423:752-765(2012) [PubMed] [Europe PMC] [Abstract]
- "Structural and functional analysis of the C-terminal domain of Nup358/RanBP2."J. Mol. Biol. 425:1318-1329(2013) [PubMed] [Europe PMC] [Abstract]
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