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Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1)

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CLEC15A; MAFA; MAFA-2F1; MAFA-L; C-Type Lectin Domain Family 15,Member A; ITIM-containing receptor MAFA-L; MAFA-like receptor; Mast cell function-associated antigen

Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1)
CCC E243
HGNC 6380
MGI 1355294
PubMed 23089397
RGD 61978
UniProt Q96E93
Wiki KLRG1
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity.
Killer cell lectin-like receptor subfamily G member 1 is a proteinelongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily G, Member 1 (KLRG1) ELISA Kit Customized Service Offer
  1. "Human MAFA has alternatively spliced variants."Biochim. Biophys. Acta 1399:209-212(1998) [PubMed] [Europe PMC] [Abstract]
  2. "MAFA-L, an ITIM-containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells."Eur. J. Immunol. 28:3755-3762(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Expression of killer cell lectin-like receptor G1 on antigen-specific human CD8+ T lymphocytes during active, latent, and resolved infection and its relation with CD57."J. Immunol. 174:6088-6094(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Tumor-associated E-cadherin mutations affect binding to the killer cell lectin-like receptor G1 in humans."J. Immunol. 179:1022-1029(2007) [PubMed] [Europe PMC] [Abstract]
  7. "Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition."Immunity 31:35-46(2009) [PubMed] [Europe PMC] [Abstract]