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Prominin 2 (PROM2)

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PROML2; Prominin-like protein 2

Prominin 2 (PROM2)
CCC E278
HGNC 20685
MGI 2138997
PubMed 19302789
RGD 621435
UniProt Q8N271
Prominin 2is a member of the prominin family of pentaspan membrane glycoproteins. The encoded protein localizes to basal epithelial cells and may be involved in the organization of plasma membrane microdomains. Alternative splicing results in multiple transcript variants.Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells
Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prominin 2 (PROM2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prominin 2 (PROM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prominin 2 (PROM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prominin 2 (PROM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prominin 2 (PROM2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prominin 2 (PROM2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prominin 2 (PROM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prominin 2 (PROM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prominin 2 (PROM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prominin 2 (PROM2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prominin 2 (PROM2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prominin 2 (PROM2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prominin 2 (PROM2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prominin 2 (PROM2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prominin 2 (PROM2) ELISA Kit Customized Service Offer
  1. "Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins."J. Biol. Chem. 278:8586-8596(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Identification and characterization of a novel testosterone-regulated prominin-like gene in the rat ventral prostate."Endocrinology 143:4788-4796(2002) [PubMed] [Europe PMC] [Abstract]
  7. "An ultrastructural and immunohistochemical study of a combined submucosal granular cell tumor and lipoma of the colon showing a unique nodule-in-nodule structure: putative implication of CD34 or prominin-2-positive stromal cells in its histopathogenesis."Virchows Arch. 449:137-139(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Differential expression of prominin-1 (CD133) and prominin-2 in major cephalic exocrine glands of adult mice."Histochem. Cell Biol. 128:409-419(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]