Rac-GTPase Activating Protein 1 (RACGAP1)

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HsCYK-4; ID-GAP; MgcRacGAP; Male germ cell RacGap

Rac-GTPase Activating Protein 1 (RACGAP1)
The predicted 527-amino acid RACGAP1 protein has a large N-terminal region containing a protein kinase C -like cysteine-rich motif. The authors determined that RACGAP1 shares highest homology with the Drosophila RnRacGAP and the chimerins of rat and human. Functional analysis showed that the GAP domain of RACGAP1 exhibits strong GAP activity towards CDC42, RAC1, and RAC2. Northern blot analysis detected an approximately 3.2-kb RACGAP1 transcript that was most abundantly expressed in testis, with low expression in most other tissues. Western blot analysis detected a RACGAP1 protein of 58 kD in testis extracts. In situ hybridization showed that RACGAP1 expression is restricted to germ cells in mature testis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE293Hu01 Recombinant Rac-GTPase Activating Protein 1 (RACGAP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE293Hu01 Polyclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) WB; IHC; ICC; IP.
MAE293Hu21 Monoclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) WB; IHC; ICC; IP.
Assay Kits SEE293Hu ELISA Kit for Rac-GTPase Activating Protein 1 (RACGAP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rac-GTPase Activating Protein 1 (RACGAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) Polyclonal Antibody Customized Service Offer
Assay Kits SEE293Mu ELISA Kit for Rac-GTPase Activating Protein 1 (RACGAP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rac-GTPase Activating Protein 1 (RACGAP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rac-GTPase Activating Protein 1 (RACGAP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rac-GTPase Activating Protein 1 (RACGAP1) ELISA Kit Customized Service Offer
  1. "MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells."Blood 96:2116-2124(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract].
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] and Testis.
  5. "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract]