The predicted 527-amino acid RACGAP1 protein has a large N-terminal region containing a protein kinase C -like cysteine-rich motif. The authors determined that RACGAP1 shares highest homology with the Drosophila RnRacGAP and the chimerins of rat and human. Functional analysis showed that the GAP domain of RACGAP1 exhibits strong GAP activity towards CDC42, RAC1, and RAC2. Northern blot analysis detected an approximately 3.2-kb RACGAP1 transcript that was most abundantly expressed in testis, with low expression in most other tissues. Western blot analysis detected a RACGAP1 protein of 58 kD in testis extracts. In situ hybridization showed that RACGAP1 expression is restricted to germ cells in mature testis.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE293Hu01 | Recombinant Rac-GTPase Activating Protein 1 (RACGAP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAE293Hu01 | Polyclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) | WB; IHC; ICC; IP. |
MAE293Hu21 | Monoclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) | WB; IHC; ICC; IP. | |
Assay Kits | SEE293Hu | ELISA Kit for Rac-GTPase Activating Protein 1 (RACGAP1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Rac-GTPase Activating Protein 1 (RACGAP1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEE293Mu | ELISA Kit for Rac-GTPase Activating Protein 1 (RACGAP1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Rac-GTPase Activating Protein 1 (RACGAP1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Rac-GTPase Activating Protein 1 (RACGAP1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Rac-GTPase Activating Protein 1 (RACGAP1) | ELISA Kit Customized Service Offer |
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