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Rho GTPase Activating Protein 19 (ARHGAP19)

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Rho GTPase Activating Protein 19 (ARHGAP19)
CCC E315
HGNC 23724
MGI 1918335
PubMed 24259668
UniProt Q14CB8
Wiki ARHGAP19
Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases, which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression. By large-scale sequencing of a human fetal brain cDNA library, Lv et al. (2007) cloned ARHGAP19.
The putative 494-amino acid protein has a calculated molecular mass of 55.8 kD and contains a central RhoGAP domain and 2 nuclear localization signals. RT-PCR analysis of human tissues detected strong expression in fetal heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, but only weak expression in adult pancreas, spleen, thymus, and ovary. Immunofluorescence localized ARHGAP19 to the nucleus in human embryonic kidney cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho GTPase Activating Protein 19 (ARHGAP19) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho GTPase Activating Protein 19 (ARHGAP19) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho GTPase Activating Protein 19 (ARHGAP19) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho GTPase Activating Protein 19 (ARHGAP19) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho GTPase Activating Protein 19 (ARHGAP19) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho GTPase Activating Protein 19 (ARHGAP19) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho GTPase Activating Protein 19 (ARHGAP19) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho GTPase Activating Protein 19 (ARHGAP19) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho GTPase Activating Protein 19 (ARHGAP19) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho GTPase Activating Protein 19 (ARHGAP19) ELISA Kit Customized Service Offer
  1. "Sequence analysis of a human RhoGAP domain-containing gene and characterization of its expression in human multiple tissues."DNA Seq. 18:184-189(2007) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones."DNA Res. 10:49-57(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]