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Plakophilin 3 (PKP3)

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Plakophilin 3 (PKP3)
CCC E340
HGNC 9025
MGI 1891830
PubMed 22223854
RGD 1309133
UniProt Q9Y446
Wiki PKP3
Plakophilin-3 is a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways.A PKP3 cDNA, cloned from a size-selected cDNA library from a CaCo-2 cell line, encodes a deduced 797-amino acid protein with a calculated molecular mass of 87.081 kD. Found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines. Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Plakophilin 3 (PKP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Plakophilin 3 (PKP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Plakophilin 3 (PKP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Plakophilin 3 (PKP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Plakophilin 3 (PKP3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Plakophilin 3 (PKP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Plakophilin 3 (PKP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Plakophilin 3 (PKP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Plakophilin 3 (PKP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Plakophilin 3 (PKP3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Plakophilin 3 (PKP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Plakophilin 3 (PKP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Plakophilin 3 (PKP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Plakophilin 3 (PKP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Plakophilin 3 (PKP3) ELISA Kit Customized Service Offer
  1. "Plakophilin 3 -- a novel cell-type-specific desmosomal plaque protein."Differentiation 64:291-306(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Plakophilin-3, a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells."J. Cell Sci. 112:2265-2276(1999) [PubMed] [Europe PMC] [Abstract]
  3. "An alternative promoter of the human plakophilin-3 gene controls the expression of the new isoform PKP3b."Cell Tissue Res. 355:143-162(2014) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." Genome Res. 16:55-65(2006) [PubMed] [Europe PMC] [Abstract]
  6. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]