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Glucose Transporter 9 (GLUT9)

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SLC2A9; GLUTX; URATv1; Solute Carrier Family 2 Member 9,Facilitated Glucose Transporter; Urate Voltage-Driven Efflux Transporter 1

Glucose Transporter 9 (GLUT9)
CCC E357
HGNC 13446
MGI 2152844
PubMed 17997608
RGD 1597012
UniProt Q9NRM0
Wiki SLC2A9
SLC2A9 may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.SLC2A9 has also recently been found to transport uric acid, and genetic variants of the transporter have been linked to increased risk of development of both hyperuricemia and gout.
Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Both isoforms are detected in kidney membrane (at protein level).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glucose Transporter 9 (GLUT9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glucose Transporter 9 (GLUT9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glucose Transporter 9 (GLUT9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glucose Transporter 9 (GLUT9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glucose Transporter 9 (GLUT9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glucose Transporter 9 (GLUT9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glucose Transporter 9 (GLUT9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glucose Transporter 9 (GLUT9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glucose Transporter 9 (GLUT9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glucose Transporter 9 (GLUT9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glucose Transporter 9 (GLUT9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glucose Transporter 9 (GLUT9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glucose Transporter 9 (GLUT9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glucose Transporter 9 (GLUT9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glucose Transporter 9 (GLUT9) ELISA Kit Customized Service Offer
  1. "Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9)."Genomics 66:217-220(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human articular chondrocytes express three facilitative glucose transporter isoforms: GLUT1, GLUT3 and GLUT9."Cell Biol. Int. 26:297-300(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Identification and characterization of human glucose transporter-like protein-9 (GLUT9): alternative splicing alters trafficking."J. Biol. Chem. 279:16229-16236(2004) [PubMed] [Europe PMC] [Abstract]
  6. "SLC2A9 influences uric acid concentrations with pronounced sex-specific effects."Nat. Genet. 40:430-436(2008) [PubMed] [Europe PMC] [Abstract]
  7. "SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout." Nat. Genet. 40:437-442(2008) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  9. "Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells."PLoS ONE 9:E84996-E84996(2014) [PubMed] [Europe PMC] [Abstract]
  10. "Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia."Am. J. Hum. Genet. 83:744-751(2008) [PubMed] [Europe PMC] [Abstract]
  11. ErratumAm. J. Hum. Genet. 83:795-795(2008)
  12. "Homozygous SLC2A9 mutations cause severe renal hypouricemia."J. Am. Soc. Nephrol. 21:64-72(2010) [PubMed] [Europe PMC] [Abstract]
  13. "Two novel homozygous SLC2A9 mutations cause renal hypouricemia type 2."Nephrol. Dial. Transplant. 27:1035-1041(2012) [PubMed] [Europe PMC] [Abstract]