Extraneuronal Monoamine Transporter (EMT)
[Edit]SLC22A3; OCT3; EMTH; Solute Carrier Family 22 Member 3; Organic cation transporter 3
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Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A3 is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.
The SLC22A3 gene encodes a deduced 556-amino acid protein containing 12 transmembrane segments. Expression analysis showed uptake of known catecholamine substrates by SLC22A3. RT-PCR analysis detected SLC22A3 expression in brain cortex, heart, and liver.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Extraneuronal Monoamine Transporter (EMT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Extraneuronal Monoamine Transporter (EMT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Extraneuronal Monoamine Transporter (EMT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Extraneuronal Monoamine Transporter (EMT) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Extraneuronal Monoamine Transporter (EMT) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Extraneuronal Monoamine Transporter (EMT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Extraneuronal Monoamine Transporter (EMT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Extraneuronal Monoamine Transporter (EMT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Extraneuronal Monoamine Transporter (EMT) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Extraneuronal Monoamine Transporter (EMT) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Extraneuronal Monoamine Transporter (EMT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Extraneuronal Monoamine Transporter (EMT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Extraneuronal Monoamine Transporter (EMT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Extraneuronal Monoamine Transporter (EMT) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Extraneuronal Monoamine Transporter (EMT) | ELISA Kit Customized Service Offer |
- "Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter."Nat. Neurosci. 1:349-351(1998) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
- "Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27."Genomics 55:209-218(1999) [PubMed] [Europe PMC] [Abstract]
- "Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney."Am. J. Physiol. 279:F449-F458(2000) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]