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Peroxisomal Membrane Protein 34kDa (PMP34)

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SLC25A17; PXMP34; Solute Carrier Family 25 Member 17; 34 kDa peroxisomal membrane protein

Peroxisomal Membrane Protein 34kDa (PMP34)
CCC E467
HGNC 10987
MGI 1342248
PubMed 22185573
RGD 1311498
UniProt O43808
Wiki SLC25A17
SLC25A17 is a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers.The deduced 307-amino acid protein has a calculated molecular mass of 34.5 kD and contains 6 membrane-spanning regions. Wylin et al. (1998) deduced the mouse sequence by database analysis and found that both the human and mouse proteins share 33% identity with the yeast protein. By RT-PCR, using primers specified for the mouse sequence, they identified a 233-bp transcript in human liver and in all rat and mouse tissues examined. By fluorescence microscopy of human hepatoma cells and mouse fibroblasts transfected with a plasmid encoding a fluorescence-tagged fusion protein, Wylin et al. (1998) found that the protein colocalizes with the dimeric peroxisomal thiolase.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE467Hu01 Recombinant Peroxisomal Membrane Protein 34kDa (PMP34) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Peroxisomal Membrane Protein 34kDa (PMP34) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peroxisomal Membrane Protein 34kDa (PMP34) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peroxisomal Membrane Protein 34kDa (PMP34) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peroxisomal Membrane Protein 34kDa (PMP34) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peroxisomal Membrane Protein 34kDa (PMP34) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peroxisomal Membrane Protein 34kDa (PMP34) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peroxisomal Membrane Protein 34kDa (PMP34) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peroxisomal Membrane Protein 34kDa (PMP34) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peroxisomal Membrane Protein 34kDa (PMP34) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peroxisomal Membrane Protein 34kDa (PMP34) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peroxisomal Membrane Protein 34kDa (PMP34) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peroxisomal Membrane Protein 34kDa (PMP34) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peroxisomal Membrane Protein 34kDa (PMP34) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peroxisomal Membrane Protein 34kDa (PMP34) ELISA Kit Customized Service Offer
  1. "Identification and characterization of human PMP34, a protein closely related to the peroxisomal integral membrane protein PMP47 of Candida boidinii."Eur. J. Biochem. 258:332-338(1998) [PubMed] [Europe PMC] [Abstract]
  2. "A genome annotation-driven approach to cloning the human ORFeome."Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of human chromosome 22." Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis."J. Cell Biol. 148:931-944(2000) [PubMed] [Europe PMC] [Abstract]
  7. "Topogenesis of peroxisomal membrane protein requires a short, positively charged intervening-loop sequence and flanking hydrophobic segments: study using human membrane protein PMP34."J. Biol. Chem. 276:9375-9382(2001) [PubMed] [Europe PMC] [Abstract]
  8. "Multiple distinct targeting signals in integral peroxisomal membrane proteins."J. Cell Biol. 153:1141-1150(2001) [PubMed] [Europe PMC] [Abstract]
  9. "Identification of human PMP34 as a peroxisomal ATP transporter."Biochem. Biophys. Res. Commun. 299:494-497(2002) [PubMed] [Europe PMC] [Abstract]
  10. "PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins."J. Cell Biol. 164:57-67(2004) [PubMed] [Europe PMC] [Abstract]
  11. "The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+."Biochem. J. 443:241-247(2012) [PubMed] [Europe PMC] [Abstract]