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Solute Carrier Family 35, Member B4 (SLC35B4)

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YEA; YEA4; UDP-Xylose And UDP-N-Acetylglucosamine Transporter; YEA4 homolog

Solute Carrier Family 35, Member B4 (SLC35B4)
CCC E499
HGNC 20584
MGI 1931249
PubMed 21507882
RGD 1308985
UniProt Q969S0
Wiki SLC35B4
Glycosyltransferases, such as SLC35B4, transport nucleotide sugars from the cytoplasm where they are synthesized, to the Golgi apparatus where they are utilized in the synthesis of glycoproteins, glycolipids, and proteoglycans.
By database analysis, followed by PCR amplification, Ashikov et al. (2005) cloned SLC35B4. The deduced 331-amino acid protein has 10 transmembrane domains and a calculated molecular mass of 37.4 kD. Epitope-tagged SLC35B4 localized to the Golgi apparatus of transfected Chinese hamster ovary cells. By assaying Golgi-rich microsomal fractions of transfected yeast cells, Ashikov et al. (2005) showed that SLC35B4 mediated the uptake of both UDP-xylose and UDP-N-acetylglucosamine.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 35, Member B4 (SLC35B4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 35, Member B4 (SLC35B4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 35, Member B4 (SLC35B4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 35, Member B4 (SLC35B4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 35, Member B4 (SLC35B4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 35, Member B4 (SLC35B4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 35, Member B4 (SLC35B4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 35, Member B4 (SLC35B4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 35, Member B4 (SLC35B4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 35, Member B4 (SLC35B4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 35, Member B4 (SLC35B4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 35, Member B4 (SLC35B4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 35, Member B4 (SLC35B4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 35, Member B4 (SLC35B4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 35, Member B4 (SLC35B4) ELISA Kit Customized Service Offer
  1. "The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine."J. Biol. Chem. 280:27230-27235(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]