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Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1)

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COLGALT1; Procollagen galactosyltransferase 1; Hydroxylysine galactosyltransferase 1; Collagen beta(1-O)galactosyltransferase 1

Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1)
CCC E533
HGNC 26182
MGI 1924348
PubMed 19075007
RGD 1309002
UniProt Q8NBJ5
Recombinant GLT25D1 and GLT25D2 enzymes showed a strong galactosyltransferase activity toward various types of collagen and toward the serum mannose-binding lectin MBL, which contains a collagen domain. Amino acid analysis of the products of GLT25D1 and GLT25D2 reactions confirmed the transfer of galactose to hydroxylysine residues.
The GLT25D1 gene is constitutively expressed in human tissues, whereas the GLT25D2 gene is expressed only at low levels in the nervous system. The GLT25D1 and GLT25D2 enzymes are similar to CEECAM1. The GLT25D1 and GLT25D2 genes now allow addressing of the biological significance of collagen glycosylation and the importance of this posttranslational modification in the etiology of connective tissue disorders.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycosyltransferase 25 Domain Containing Protein 1 (GLT25D1) ELISA Kit Customized Service Offer
  1. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Core glycosylation of collagen is initiated by two beta(1-O)galactosyltransferases."Mol. Cell. Biol. 29:943-952(2009) [PubMed] [Europe PMC] [Abstract]
  6. "The human collagen beta(1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum localized protein."BMC Cell Biol. 11:33-33(2010) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]