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TATA Box Binding Protein Associated Factor 3 (TAF3)

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TAF140; TAFII140; Transcription Initiation Factor TFIID Subunit 3; •140 kDa TATA box-binding protein-associated factor; Transcription initiation factor TFIID 140 kDa subunit

TATA Box Binding Protein Associated Factor 3 (TAF3)
CCC E553
HGNC 17303
MGI 2388097
PubMed 23452851
UniProt Q5VWG9
Wiki TAF3
The highly conserved RNA polymerase II transcription factor TFIID comprises the TATA box-binding protein (TBP) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors. By EST database searching for sequences similar to the histone fold domain (HFD) of yeast Tafii47, followed by probing a HeLa cell cDNA library, Gangloff et al. (2001) obtained a partial cDNA encoding TAF3, which they termed TAFII140. The deduced 727-amino acid protein contains an N-terminal HFD and is highly homologous to mouse Tafii140. The 932-amino acid mouse protein has a C-terminal plant homeodomain (PHD) finger, and genomic database analysis suggested that this motif is present in human TAF3.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TATA Box Binding Protein Associated Factor 3 (TAF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TATA Box Binding Protein Associated Factor 3 (TAF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TATA Box Binding Protein Associated Factor 3 (TAF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 3 (TAF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 3 (TAF3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TATA Box Binding Protein Associated Factor 3 (TAF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TATA Box Binding Protein Associated Factor 3 (TAF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TATA Box Binding Protein Associated Factor 3 (TAF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 3 (TAF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 3 (TAF3) ELISA Kit Customized Service Offer
  1. "The TFIID components human TAFII140 and Drosophila BIP2 (TAFII155) are novel metazoan homologues of yeast TAFII47 containing a histone fold and a PHD finger."Mol. Cell. Biol. 21:5109-5121(2001) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]