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TATA Box Binding Protein Associated Factor 10 (TAF10)

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TAF2A; TAF2H; TAFII30; STAF28; Transcription Initiation Factor TFIID Subunit 10; Transcription initiation factor TFIID 30 kDa subunit

TATA Box Binding Protein Associated Factor 10 (TAF10)
CCC E560
HGNC 11543
MGI 1346320
PubMed 15099517
RGD 1305907
UniProt Q12962
Wiki TAF10
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.
TAF10 encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TATA Box Binding Protein Associated Factor 10 (TAF10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TATA Box Binding Protein Associated Factor 10 (TAF10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TATA Box Binding Protein Associated Factor 10 (TAF10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 10 (TAF10) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 10 (TAF10) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TATA Box Binding Protein Associated Factor 10 (TAF10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TATA Box Binding Protein Associated Factor 10 (TAF10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TATA Box Binding Protein Associated Factor 10 (TAF10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 10 (TAF10) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 10 (TAF10) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TATA Box Binding Protein Associated Factor 10 (TAF10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TATA Box Binding Protein Associated Factor 10 (TAF10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TATA Box Binding Protein Associated Factor 10 (TAF10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 10 (TAF10) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 10 (TAF10) ELISA Kit Customized Service Offer
  1. "Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor."Cell 79:107-117(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Organization and chromosomal localization of the gene (TAF2H) encoding the human TBP-associated factor II 30 (TAFII30)."Genomics 29:269-272(1995) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Histone-like TAFs within the PCAF histone acetylase complex."Cell 94:35-44(1998) [PubMed] [Europe PMC] [Abstract]
  5. "Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo."Mol. Cell. Biol. 21:6782-6795(2001) [PubMed] [Europe PMC] [Abstract]
  6. "The 400 kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily."Mol. Cell 2:869-875(1998) [PubMed] [Europe PMC] [Abstract]
  7. "Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction."J. Biol. Chem. 274:18285-18289(1999) [PubMed] [Europe PMC] [Abstract]
  8. "The TFIID components human TAFII140 and Drosophila BIP2 (TAFII155) are novel metazoan homologues of yeast TAFII47 containing a histone fold and a PHD finger."Mol. Cell. Biol. 21:5109-5121(2001) [PubMed] [Europe PMC] [Abstract]
  9. "Gene-specific modulation of TAF10 function by SET9-mediated methylation."Mol. Cell 14:175-182(2004) [PubMed] [Europe PMC] [Abstract]
  10. "Structural basis for the methylation site specificity of SET7/9."Nat. Struct. Mol. Biol. 13:140-146(2006) [PubMed] [Europe PMC] [Abstract]
  11. "Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis."Proteomics 3:217-223(2003) [PubMed] [Europe PMC] [Abstract]
  12. "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing."Mol. Cell 29:92-101(2008) [PubMed] [Europe PMC] [Abstract]
  13. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]