B-Cell CLL/Lymphoma 11A (Bcl11A)
[Edit]BCL11A-L; BCL11A-S; BCL11A-XL; CTIP1; EVI9; Ecotropic Viral Integration Site 9; COUP-TF-interacting protein 1; Ecotropic viral integration site 9 homolog; Zinc finger protein 856
B-cell lymphoma/leukemia 11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Five alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been reported. Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes, and megakaryoctes.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE578Hu01 | Recombinant B-Cell CLL/Lymphoma 11A (Bcl11A) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAE578Hu21 | Monoclonal Antibody to B-Cell CLL/Lymphoma 11A (Bcl11A) | WB; IHC; ICC; IP. |
PAE578Hu01 | Polyclonal Antibody to B-Cell CLL/Lymphoma 11A (Bcl11A) | WB; IHC; ICC; IP. | |
Assay Kits | SEE578Hu | ELISA Kit for B-Cell CLL/Lymphoma 11A (Bcl11A) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant B-Cell CLL/Lymphoma 11A (Bcl11A) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to B-Cell CLL/Lymphoma 11A (Bcl11A) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to B-Cell CLL/Lymphoma 11A (Bcl11A) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for B-Cell CLL/Lymphoma 11A (Bcl11A) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for B-Cell CLL/Lymphoma 11A (Bcl11A) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant B-Cell CLL/Lymphoma 11A (Bcl11A) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to B-Cell CLL/Lymphoma 11A (Bcl11A) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to B-Cell CLL/Lymphoma 11A (Bcl11A) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for B-Cell CLL/Lymphoma 11A (Bcl11A) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for B-Cell CLL/Lymphoma 11A (Bcl11A) | ELISA Kit Customized Service Offer |
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