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B-Cell CLL/Lymphoma 7A (Bcl7A)

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BCL7

B-Cell CLL/Lymphoma 7A (Bcl7A)
CCC E587
HGNC 1004
MGI 1924295
PubMed 23043359
UniProt Q4VC05
Bcl7A is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
B-cell CLL/lymphoma refers to a family of genes associated with certain types of lymphoma and leukemia.Although named for B-cell chronic lymphocytic leukemia, they can be associated with other malignancies.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE587Hu01 Recombinant B-Cell CLL/Lymphoma 7A (Bcl7A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE587Hu01 Polyclonal Antibody to B-Cell CLL/Lymphoma 7A (Bcl7A) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for B-Cell CLL/Lymphoma 7A (Bcl7A) CLIA Kit Customized Service Offer
n/a ELISA Kit for B-Cell CLL/Lymphoma 7A (Bcl7A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant B-Cell CLL/Lymphoma 7A (Bcl7A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to B-Cell CLL/Lymphoma 7A (Bcl7A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to B-Cell CLL/Lymphoma 7A (Bcl7A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for B-Cell CLL/Lymphoma 7A (Bcl7A) CLIA Kit Customized Service Offer
n/a ELISA Kit for B-Cell CLL/Lymphoma 7A (Bcl7A) ELISA Kit Customized Service Offer
  1. "Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon."Blood 87:3124-3134(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]