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Minichromosome Maintenance Deficient 5 (MCM5)

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CDC46; P1-CDC46; Cell Division Cycle 46; DNA replication licensing factor MCM5

Minichromosome Maintenance Deficient 5 (MCM5)
CCC E651
HGNC 6948
MGI 103197
PubMed 21233845
RGD 1306616
UniProt P33992
Wiki MCM5
MCM5 isa protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.Depletion of ASF1 by RNA interference impeded DNA unwinding at replication sites, and similar defects arose from overproduction of new histone H3-H4 that compromised ASF1 function.ASF1, as a histone acceptor and donor, handles parental and new histones at the replication fork via an ASF1-(H3-H4)-MCM2-7 intermediate and thus provides a means to fine-tune replication fork progression and histone supply and demand.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE651Hu01 Recombinant Minichromosome Maintenance Deficient 5 (MCM5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE651Hu01 Polyclonal Antibody to Minichromosome Maintenance Deficient 5 (MCM5) WB; IHC; ICC; IP.
MAE651Hu21 Monoclonal Antibody to Minichromosome Maintenance Deficient 5 (MCM5) WB; IHC; ICC; IP.
Assay Kits SEE651Hu ELISA Kit for Minichromosome Maintenance Deficient 5 (MCM5) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Minichromosome Maintenance Deficient 5 (MCM5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Minichromosome Maintenance Deficient 5 (MCM5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Minichromosome Maintenance Deficient 5 (MCM5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Minichromosome Maintenance Deficient 5 (MCM5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Minichromosome Maintenance Deficient 5 (MCM5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Minichromosome Maintenance Deficient 5 (MCM5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Minichromosome Maintenance Deficient 5 (MCM5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Minichromosome Maintenance Deficient 5 (MCM5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Minichromosome Maintenance Deficient 5 (MCM5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Minichromosome Maintenance Deficient 5 (MCM5) ELISA Kit Customized Service Offer
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