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Cell Division Cycle Protein 27 (CDC27)

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APC3; ANAPC3; CDC27Hs; HNUC; Anaphase Promoting Complex Subunit 3

Cell Division Cycle Protein 27 (CDC27)
CCC E660
HGNC 1728
MGI 102685
PubMed 22280307
RGD 1304921
UniProt P30260
Wiki CDC27
CDC27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins.
This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE660Hu01 Recombinant Cell Division Cycle Protein 27 (CDC27) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE660Hu01 Polyclonal Antibody to Cell Division Cycle Protein 27 (CDC27) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Cell Division Cycle Protein 27 (CDC27) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cell Division Cycle Protein 27 (CDC27) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cell Division Cycle Protein 27 (CDC27) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cell Division Cycle Protein 27 (CDC27) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cell Division Cycle Protein 27 (CDC27) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cell Division Cycle Protein 27 (CDC27) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cell Division Cycle Protein 27 (CDC27) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cell Division Cycle Protein 27 (CDC27) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cell Division Cycle Protein 27 (CDC27) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cell Division Cycle Protein 27 (CDC27) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cell Division Cycle Protein 27 (CDC27) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cell Division Cycle Protein 27 (CDC27) ELISA Kit Customized Service Offer
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  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
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  15. "Molecular basis for the association of microcephalin (MCPH1) protein with the cell division cycle protein 27 (Cdc27) subunit of the anaphase-promoting complex."J. Biol. Chem. 287:2854-2862(2012) [PubMed] [Europe PMC] [Abstract]
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