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Tubulin Beta 3 (TUBb3)

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MC1R; TUBB4; Tubulin beta-4 chain

Tubulin Beta 3 (TUBb3)
CCC E711
HGNC 20772
MGI 107813
PubMed 22684772
RGD 628595
UniProt Q13509
Wiki TUBB3
TUBB3 expression in several human cell lines, but not in a paclitaxel-resistant cell line. RNA interference revealed that HIF1A mediated hypoxia-induced TUBB3 expression. Chromatin immunoprecipitation analysis showed that HIF1A bound an HIF1A-binding site in the 5-prime flanking region of the TUBB3 gene. Methylation of an enhancer in the 3-prime flanking region abolished hypoxia-induced TUBB3 expression. Much lower Tubb3 levels were detected in all other adult mouse tissues examined except brain, where expression was even lower. Chromatin immunoprecipitation analysis showed that HIF1A bound an HIF1A-binding site in the 5-prime flanking region of the TUBB3 gene. Methylation of an enhancer in the 3-prime flanking region abolished hypoxia-induced TUBB3 expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE711Hu01 Recombinant Tubulin Beta 3 (TUBb3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE711Hu01 Polyclonal Antibody to Tubulin Beta 3 (TUBb3) WB; IHC; ICC; IP.
LAE711Hu81 FITC-Linked Polyclonal Antibody to Tubulin Beta 3 (TUBb3) WB; IHC; ICC; IF.
LAE711Hu71 Biotin-Linked Polyclonal Antibody to Tubulin Beta 3 (TUBb3) WB; IHC; ICC.
MAE711Hu21 Monoclonal Antibody to Tubulin Beta 3 (TUBb3) WB; IHC; ICC; IP.
Assay Kits SEE711Hu ELISA Kit for Tubulin Beta 3 (TUBb3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tubulin Beta 3 (TUBb3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tubulin Beta 3 (TUBb3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulin Beta 3 (TUBb3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulin Beta 3 (TUBb3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulin Beta 3 (TUBb3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tubulin Beta 3 (TUBb3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tubulin Beta 3 (TUBb3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tubulin Beta 3 (TUBb3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tubulin Beta 3 (TUBb3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tubulin Beta 3 (TUBb3) ELISA Kit Customized Service Offer
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  5. , Submitted (DEC-2008) to UniProtKB
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