Nuclear Receptor Interacting Protein 3 (NRIP3)

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C11orf14; Sarcoma antigen NY-SAR-105

Nuclear Receptor Interacting Protein 3 (NRIP3)
NRIP3: a novel translocation partner of MLL detected in a pediatric acute myeloid leukemia with complex chromosome 11 rearrangements. Using microarray and RT-PCR analyses, Zhong et al. (2007) found that the NRIP3 gene was downregulated in all 9 nonsmall cell lung cancer (NSCLC) cell lines examined compared with normal controls.
Semiquantitative RT-PCR showed downregulation of NRIP3 in 4 of 8 lung tumor samples compared with adjacent normal tissue. The promoter region of NRIP3 was highly methylated in 1 NSCLC cell line and partially methylated in 4 others, and treatment of several NSCLC cell lines with a combination of DNA methylation and histone deacetylase inhibitors restored NRIP3 expression.the promoter region of the NRIP3 gene contains a CpG island.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE793Hu01 Recombinant Nuclear Receptor Interacting Protein 3 (NRIP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Receptor Interacting Protein 3 (NRIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Receptor Interacting Protein 3 (NRIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) ELISA Kit Customized Service Offer
  1. "Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7."Cytogenet. Cell Genet. 93:284-290(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Immunomic analysis of human sarcoma."Proc. Natl. Acad. Sci. U.S.A. 100:2651-2656(2003) [PubMed] [Europe PMC] [Abstract]