NRIP3: a novel translocation partner of MLL detected in a pediatric acute myeloid leukemia with complex chromosome 11 rearrangements. Using microarray and RT-PCR analyses, Zhong et al. (2007) found that the NRIP3 gene was downregulated in all 9 nonsmall cell lung cancer (NSCLC) cell lines examined compared with normal controls.
Semiquantitative RT-PCR showed downregulation of NRIP3 in 4 of 8 lung tumor samples compared with adjacent normal tissue. The promoter region of NRIP3 was highly methylated in 1 NSCLC cell line and partially methylated in 4 others, and treatment of several NSCLC cell lines with a combination of DNA methylation and histone deacetylase inhibitors restored NRIP3 expression.the promoter region of the NRIP3 gene contains a CpG island.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE793Hu01 | Recombinant Nuclear Receptor Interacting Protein 3 (NRIP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Nuclear Receptor Interacting Protein 3 (NRIP3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Nuclear Receptor Interacting Protein 3 (NRIP3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Nuclear Receptor Interacting Protein 3 (NRIP3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Nuclear Receptor Interacting Protein 3 (NRIP3) | ELISA Kit Customized Service Offer |
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