Nuclear Receptor Coactivator 3 (NCOA3)
[Edit]RAC3; ACTR; AIB1; CAGH16; CTG26; SRC3; TNRC14; TNRC16; TRAM1; pCIP; Amplified In Breast 1; Steroid Receptor Coactivator-3 ; Thyroid Hormone Receptor Activator Molecule 1
NCOA3 is a transcriptional coactivator protein which contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity. NCOA3 is recruited to DNA promotion sites by ligand activated nuclear receptors. NCOA3 in turn acylates histones which makes downsteam DNA more accessible to transcription. Hence NCOA3 assists nuclear receptors in the upregulation of gene expression.
This variant, which they called AIB-delta-3, encodes a 130-kD protein lacking the N-terminal basic helix-loop-helix domain and the first of the 2 PAS dimerization domains of full-length AIB1. Northern and Western blot analyses detected higher AIB-delta-3 expression in breast tumor samples and cell lines than in normal breast tissue.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE798Hu01 | Recombinant Nuclear Receptor Coactivator 3 (NCOA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAE798Hu21 | Monoclonal Antibody to Nuclear Receptor Coactivator 3 (NCOA3) | WB; IHC; ICC; IP. |
PAE798Hu01 | Polyclonal Antibody to Nuclear Receptor Coactivator 3 (NCOA3) | WB; ICC; IHC-P; IHC-F; ELISA. | |
Assay Kits | SEE798Hu | ELISA Kit for Nuclear Receptor Coactivator 3 (NCOA3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Nuclear Receptor Coactivator 3 (NCOA3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Nuclear Receptor Coactivator 3 (NCOA3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Nuclear Receptor Coactivator 3 (NCOA3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Nuclear Receptor Coactivator 3 (NCOA3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Nuclear Receptor Coactivator 3 (NCOA3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE798Ra01 | Recombinant Nuclear Receptor Coactivator 3 (NCOA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAE798Ra21 | Monoclonal Antibody to Nuclear Receptor Coactivator 3 (NCOA3) | WB; IHC; ICC; IP. |
PAE798Ra01 | Polyclonal Antibody to Nuclear Receptor Coactivator 3 (NCOA3) | WB; IHC; ICC; IP. | |
Assay Kits | SEE798Ra | ELISA Kit for Nuclear Receptor Coactivator 3 (NCOA3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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