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Alcohol Dehydrogenase 2 (ADH2)

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ADH1B; Alcohol dehydrogenase subunit beta

Alcohol Dehydrogenase 2 (ADH2)
CCC E861
HGNC 250
PubMed 17963305
UniProt P00325
Wiki ADH1B
ADH2 encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism.
Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Previously ADH1B was called ADH2. There are more genes in the family of alcohol and aldehyde dehydrogenase genes. These genes are now referred to as ADH1A, ADH1C, and ADH4, ADH5, ADH6 and ADH7.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE861Hu01 Recombinant Alcohol Dehydrogenase 2 (ADH2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE861Hu01 Polyclonal Antibody to Alcohol Dehydrogenase 2 (ADH2) WB; IHC; ICC; IP.
MAE861Hu21 Monoclonal Antibody to Alcohol Dehydrogenase 2 (ADH2) WB; IHC; ICC; IP.
Assay Kits SEE861Hu ELISA Kit for Alcohol Dehydrogenase 2 (ADH2) Enzyme-linked immunosorbent assay for Antigen Detection.
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  2. ErratumProc. Natl. Acad. Sci. U.S.A. 82:5578-5578(1985)
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  5. "Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence."Proc. Natl. Acad. Sci. U.S.A. 83:634-638(1986) [PubMed] [Europe PMC] [Abstract]
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  16. "The human beta 3 alcohol dehydrogenase subunit differs from beta 1 by a Cys for Arg-369 substitution which decreases NAD(H) binding."Biochem. Biophys. Res. Commun. 146:1127-1133(1987) [PubMed] [Europe PMC] [Abstract]
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  19. "X-ray structure of human beta3beta3 alcohol dehydrogenase. The contribution of ionic interactions to coenzyme binding."J. Biol. Chem. 271:17057-17061(1996) [PubMed] [Europe PMC] [Abstract]
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