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Sorting Nexin 4 (SNX4)

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Sorting Nexin 4 (SNX4)
CCC E874
HGNC 11175
MGI 1916400
PubMed 17994011
RGD 1309763
UniProt O95219
Wiki SNX4
Sorting nexin-4 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members.
The SNX4 cDNA encodes a deduced 450-amino acid protein. Northern blot analysis detected ubiquitous expression of SNX4, with highest expression in pituitary gland, testis, and liver.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sorting Nexin 4 (SNX4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sorting Nexin 4 (SNX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sorting Nexin 4 (SNX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sorting Nexin 4 (SNX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sorting Nexin 4 (SNX4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sorting Nexin 4 (SNX4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sorting Nexin 4 (SNX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sorting Nexin 4 (SNX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sorting Nexin 4 (SNX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sorting Nexin 4 (SNX4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sorting Nexin 4 (SNX4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sorting Nexin 4 (SNX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sorting Nexin 4 (SNX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sorting Nexin 4 (SNX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sorting Nexin 4 (SNX4) ELISA Kit Customized Service Offer
  1. "Identification of a family of sorting nexin molecules and characterization of their association with receptors."Mol. Cell. Biol. 18:7278-7287(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment."Nat. Cell Biol. 9:1370-1380(2007) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]