A Kinase Anchor Protein 12 (AKAP12)
[Edit]AKAP250; Gravin; A-kinase anchor protein 250 kDa; Myasthenia gravis autoantigen
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family.
AKAP12 is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE892Hu01 | Recombinant A Kinase Anchor Protein 12 (AKAP12) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAE892Hu01 | Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for A Kinase Anchor Protein 12 (AKAP12) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for A Kinase Anchor Protein 12 (AKAP12) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant A Kinase Anchor Protein 12 (AKAP12) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for A Kinase Anchor Protein 12 (AKAP12) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for A Kinase Anchor Protein 12 (AKAP12) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant A Kinase Anchor Protein 12 (AKAP12) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for A Kinase Anchor Protein 12 (AKAP12) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for A Kinase Anchor Protein 12 (AKAP12) | ELISA Kit Customized Service Offer |
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