Ring Finger Protein 55 (RNF55)
[Edit]CBL; C-CBL; CBL2; Cas-Br-M(Murine)Ecotropic Retroviral Transforming Sequence; Casitas B-lineage Lymphoma; Proto-oncogene c-Cbl; Signal transduction protein CBL
The virus used in the experiment was a retrovirus known as Cas-Br-M, and was found to have excised approximately a third of the original c-Cbl gene from mice it was injected into. Sequencing revealed that the portion carried by the retrovirus encoded a tyrosine kinase binding domain, and that this was the oncogenic form as retroviruses carrying full-length c-Cbl did not induce tumour formation. The resultant transformed retrovirus was found to consistently induce a type of pre-B lymphoma, known as Casitas B-lineage lymphoma, in infected mice.
This domain structure and the tyrosine and serine-rich content of the protein product is typical of an "adaptor molecule" used in cell signalling pathways.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE942Hu01 | Recombinant Ring Finger Protein 55 (RNF55) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAE942Hu01 | Polyclonal Antibody to Ring Finger Protein 55 (RNF55) | WB; IHC; ICC; IP. |
Assay Kits | SEE942Hu | ELISA Kit for Ring Finger Protein 55 (RNF55) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ring Finger Protein 55 (RNF55) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ring Finger Protein 55 (RNF55) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ring Finger Protein 55 (RNF55) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ring Finger Protein 55 (RNF55) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ring Finger Protein 55 (RNF55) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ring Finger Protein 55 (RNF55) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ring Finger Protein 55 (RNF55) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ring Finger Protein 55 (RNF55) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ring Finger Protein 55 (RNF55) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ring Finger Protein 55 (RNF55) | ELISA Kit Customized Service Offer |
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