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Ribosomal Protein, Large, P2 (RPLP2)

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P2; RPP2; 60S Acidic Ribosomal Protein P2; Acidic Ribosomal Phosphoprotein P2; Renal carcinoma antigen NY-REN-44

Ribosomal Protein, Large, P2 (RPLP2)
CCC E973
HGNC 10377
MGI 1914436
PubMed 3323886
RGD 621775
UniProt P05387
Wiki RPLP2
RPLP2 encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE973Hu01 Recombinant Ribosomal Protein, Large, P2 (RPLP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE973Hu01 Polyclonal Antibody to Ribosomal Protein, Large, P2 (RPLP2) WB; IHC; ICC; IP.
Assay Kits SEE973Hu ELISA Kit for Ribosomal Protein, Large, P2 (RPLP2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein, Large, P2 (RPLP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein, Large, P2 (RPLP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein, Large, P2 (RPLP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein, Large, P2 (RPLP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein, Large, P2 (RPLP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein, Large, P2 (RPLP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein, Large, P2 (RPLP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein, Large, P2 (RPLP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein, Large, P2 (RPLP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein, Large, P2 (RPLP2) ELISA Kit Customized Service Offer
  1. "Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly."Mol. Cell. Biol. 7:4065-4074(1987) [PubMed] [Europe PMC] [Abstract]
  2. "A sequence previously identified as metastasis-related encodes an acidic ribosomal phosphoprotein, P2."Br. J. Cancer 61:83-88(1990) [PubMed] [Europe PMC] [Abstract]
  3. "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes."Genome Res. 12:379-390(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Human liver protein map: a reference database established by microsequencing and gel comparison."Electrophoresis 13:992-1001(1992) [PubMed] [Europe PMC] [Abstract]
  8. "Antigens recognized by autologous antibody in patients with renal-cell carcinoma."Int. J. Cancer 83:456-464(1999) [PubMed] [Europe PMC] [Abstract]
  9. "Identification and characterization of phosphorylated proteins in the human pituitary."Proteomics 4:587-598(2004) [PubMed] [Europe PMC] [Abstract]
  10. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  11. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  12. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  13. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  14. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  16. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  17. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  18. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  19. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  20. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  21. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  22. "Solution structure of the dimerization domain of ribosomal protein P2 provides insights for the structural organization of eukaryotic stalk."Nucleic Acids Res. 38:5206-5216(2010) [PubMed] [Europe PMC] [Abstract]
  23. "Structures of the human and Drosophila 80S ribosome."Nature 497:80-85(2013) [PubMed] [Europe PMC] [Abstract]