≡

Ribosomal Protein L8 (RPL8)

[Edit]

Ribosomal Protein L8 (RPL8)
CCC F048
HGNC 10368
MGI 1350927
PubMed 1343779
RGD 619827
UniProt P62917
Wiki RPL8
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
RPL8 encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein L8 (RPL8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein L8 (RPL8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein L8 (RPL8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein L8 (RPL8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein L8 (RPL8) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein L8 (RPL8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein L8 (RPL8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein L8 (RPL8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein L8 (RPL8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein L8 (RPL8) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein L8 (RPL8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein L8 (RPL8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein L8 (RPL8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein L8 (RPL8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein L8 (RPL8) ELISA Kit Customized Service Offer
  1. "Characterization by cDNA cloning of the mRNA of human ribosomal protein L8."Biochem. Biophys. Res. Commun. 197:1223-1228(1993) [PubMed] [Europe PMC] [Abstract]
  2. "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes."Genome Res. 12:379-390(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A map of 75 human ribosomal protein genes."Genome Res. 8:509-523(1998) [PubMed] [Europe PMC] [Abstract]
  6. "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing."J. Protein Chem. 22:249-258(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Functional implications of ribosomal protein L2 in protein biosynthesis as shown by in vivo replacement studies."Biochem. J. 331:423-430(1998) [PubMed] [Europe PMC] [Abstract]
  8. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans." Nat. Chem. Biol. 8:960-962(2012) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  12. "Structures of the human and Drosophila 80S ribosome."Nature 497:80-85(2013) [PubMed] [Europe PMC] [Abstract]