G Protein Beta 2 (GNb2)
[Edit]Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T)Beta Subunit 2; Signal-Transducing Guanine Nucleotide-Binding Regulatory Protein Beta Subunit; Transducin Beta Chain 2
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Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. GNb2 is a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. GNb2 is a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF073Hu01 | Recombinant G Protein Beta 2 (GNb2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAF073Hu01 | Polyclonal Antibody to G Protein Beta 2 (GNb2) | WB; IHC |
| Assay Kits | SEF073Hu | ELISA Kit for G Protein Beta 2 (GNb2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant G Protein Beta 2 (GNb2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to G Protein Beta 2 (GNb2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to G Protein Beta 2 (GNb2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for G Protein Beta 2 (GNb2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for G Protein Beta 2 (GNb2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant G Protein Beta 2 (GNb2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to G Protein Beta 2 (GNb2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to G Protein Beta 2 (GNb2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for G Protein Beta 2 (GNb2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for G Protein Beta 2 (GNb2) | ELISA Kit Customized Service Offer |
- "Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning."Proc. Natl. Acad. Sci. U.S.A. 84:3792-3796(1987) [PubMed] [Europe PMC] [Abstract]
- "A second form of the beta subunit of signal-transducing G proteins."Proc. Natl. Acad. Sci. U.S.A. 84:6122-6125(1987) [PubMed] [Europe PMC] [Abstract]
- "Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes."Genome Res. 8:1060-1073(1998) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]