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Replication Factor C3 (RFC3)

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RFC38; Activator 1 38 kDa subunit; Activator 1 subunit 3; Replication factor C 38 kDa subunit

Replication Factor C3 (RFC3)
CCC F079
HGNC 9971
MGI 1916513
PubMed 22328562
RGD 1306832
UniProt P40938
Wiki RFC3
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa.
RFC3 encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.Tight interfacial coordination of the ATP analog ATP-gamma-S by RFC resulted in a spiral arrangement of the ATPase domains of the clamp loader above the PCNA ring.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF079Hu01 Recombinant Replication Factor C3 (RFC3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Replication Factor C3 (RFC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Replication Factor C3 (RFC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Replication Factor C3 (RFC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Replication Factor C3 (RFC3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Replication Factor C3 (RFC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Replication Factor C3 (RFC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Replication Factor C3 (RFC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Replication Factor C3 (RFC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Replication Factor C3 (RFC3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Replication Factor C3 (RFC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Replication Factor C3 (RFC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Replication Factor C3 (RFC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Replication Factor C3 (RFC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Replication Factor C3 (RFC3) ELISA Kit Customized Service Offer
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