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17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13)

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SCDR9; SDR16C3; Short Chain Dehydrogenase/Reductase Family 16C,Member 3; Short-chain dehydrogenase/reductase 9

17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13)
CCC F179
HGNC 18685
MGI 2140804
RGD 1359553
UniProt Q7Z5P4
By database analysis using HSD17B11 as query, followed by screening a human liver cDNA library, Liu et al. (2007) isolated HSD17B13, which they called SCDR9. The predicted 300-amino acid protein has a calculated molecular mass of 33.66 kD. HSD17B13 has a conserved TGXGXXXG motif involved in NADPH binding and a YXXXK motif related to its catalytic activity.
HSD17B13 shares 78% homology with HSD17B11. PCR amplification showed that HSD17B13 was highly expressed in liver with low levels in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder, and testis. Immunofluorescence microscopy showed punctate distribution in the cytoplasm but with little overlap with an ER marker. HSD17B13 gene contains 7 exons and spans 17 kb.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) CLIA Kit Customized Service Offer
n/a ELISA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) CLIA Kit Customized Service Offer
n/a ELISA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) CLIA Kit Customized Service Offer
n/a ELISA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 13 (HSD17b13) ELISA Kit Customized Service Offer
  1. "Molecular cloning and expression analysis of a new gene for short-chain dehydrogenase/reductase 9."Acta Biochim. Pol. 54:213-218(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas."Oncogene 23:5901-5911(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]