Fucosyltransferase 5 (FUT5)
[Edit]FUC-TV; Galactoside 3-L-fucosyltransferase; Alpha-(1,3)-fucosyltransferase 5
McCurley et al. (1995) mapped FUT5 to 19p13.3 by fluorescence in situ hybridization using cosmids containing FUT6 and FUT5. The results indicated that FUT6 lies approximately 70 kb telomeric of FUT5. McCurley et al. (1995) used conventional and pulsed field gel electrophoresis mapping to total genomic DNA and large genomic clones in order to generate a fine map of the cluster of 19p FUT genes. A P1 clone indicated the gene order: cen--FUT5--FUT3--FUT6--tel. FUT5 and FUT3 are separated by 23 kb and FUT3 and FUT6 are separated by 14 kb; these data placed FUT5 and FUT6 closer together than was estimated by fluorescence in situ hybridization. The close proximity and tandem orientation of the 3 genes suggests coordinate regulation. The direction of transcription is toward the telomere in the case of all 3 genes.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPF195Hu01 | Recombinant Fucosyltransferase 5 (FUT5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Fucosyltransferase 5 (FUT5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Fucosyltransferase 5 (FUT5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Fucosyltransferase 5 (FUT5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Fucosyltransferase 5 (FUT5) | ELISA Kit Customized Service Offer |
- "Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities."J. Biol. Chem. 267:4152-4160(1992) [PubMed] [Europe PMC] [Abstract]
- "Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms."J. Biol. Chem. 270:20112-20122(1995) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]