Calcium Channel,Voltage Dependent,Alpha 2/Delta Subunit 2 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex.
Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 2 (CACNa2d2) | ELISA Kit Customized Service Offer |
- "Molecular diversity of the calcium channel alpha2delta subunit."J. Neurosci. 19:684-691(1999) [PubMed] [Europe PMC] [Abstract]
- "Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2)."J. Biol. Chem. 275:12237-12242(2000) [PubMed] [Europe PMC] [Abstract]
- "Neuronal distribution and functional characterization of the calcium channel alpha2delta-2 subunit."Eur. J. Neurosci. 12:1217-1226(2000) [PubMed] [Europe PMC] [Abstract]
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- "Calcium channel alpha2delta subunits: differential expression, function, and drug binding."J. Bioenerg. Biomembr. 35:639-647(2003) [PubMed] [Europe PMC] [Abstract]
- "CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity."Oncogene 22:615-626(2003) [PubMed] [Europe PMC] [Abstract]
- "Modulation of gating currents of the Ca(v)3.1 calcium channel by alpha 2 delta 2 and gamma 5 subunits."Arch. Biochem. Biophys. 425:207-213(2004) [PubMed] [Europe PMC] [Abstract]
- "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]