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Centrosomal Protein 170kDa (CEP170)

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FAM68A; KAB; KARP 1 Binding Protein; XRCC5 Binding Protein; KARP-1-binding protein

Centrosomal Protein 170kDa (CEP170)
CCC F274
HGNC 28920
MGI 1918348
PubMed 23087211
UniProt Q5SW79
Wiki CEP170
CEP170 is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes.
The protein interacts with the intraflagellar transport protein 81 (IFT81) and is phosphorylated by cyclin dependent kinase 1 (CDK1) and polo-like kinase 1 (PLK1), and functions in maintaining microtubule organization, cell morphology and cilium stability.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centrosomal Protein 170kDa (CEP170) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centrosomal Protein 170kDa (CEP170) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centrosomal Protein 170kDa (CEP170) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centrosomal Protein 170kDa (CEP170) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centrosomal Protein 170kDa (CEP170) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centrosomal Protein 170kDa (CEP170) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centrosomal Protein 170kDa (CEP170) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centrosomal Protein 170kDa (CEP170) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centrosomal Protein 170kDa (CEP170) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centrosomal Protein 170kDa (CEP170) ELISA Kit Customized Service Offer
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  15. "Crystal structure of a centrosomal protein 170kDA, transcript variant beta (CEP170) from Homo sapiens at 2.15 A resolution (PSI community target, Sundstrom)."Submitted (APR-2013) to the PDB data bank