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Chondroitin Polymerizing Factor (CHPF)

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CHSY2; CSS2; Chondroitin Sulfate Synthase 2; Chondroitin glucuronyltransferase 2; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II

Chondroitin Polymerizing Factor (CHPF)
CCC F287
HGNC 24291
MGI 106576
PubMed 12716890
RGD 1359458
UniProt Q8IZ52
Wiki CHPF
By database searching with the sequence of CHSY1 as probe, Kitagawa et al. (2003) isolated CHPF. The deduced 775-amino acid protein has a predicted molecular mass of approximately 85 kD and contains 3 potential N-glycosylation sites.
CHPF has a prominent N-terminal hydrophobic segment and is predicted to be a type II transmembrane protein. CHPF shares 57% and 23% sequence identity with chondroitin sulfate glucuronyltransferase (CSGlcAT) and CHSY1, respectively. Northern blot analysis detected a 3.4-kb CHPF transcript in all tissues examined except peripheral blood leukocytes; CHPF expression was detected at high levels in placenta and heart and at moderate levels in brain, skeletal muscle, kidney, and liver.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chondroitin Polymerizing Factor (CHPF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chondroitin Polymerizing Factor (CHPF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chondroitin Polymerizing Factor (CHPF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chondroitin Polymerizing Factor (CHPF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chondroitin Polymerizing Factor (CHPF) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chondroitin Polymerizing Factor (CHPF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chondroitin Polymerizing Factor (CHPF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chondroitin Polymerizing Factor (CHPF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chondroitin Polymerizing Factor (CHPF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chondroitin Polymerizing Factor (CHPF) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chondroitin Polymerizing Factor (CHPF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chondroitin Polymerizing Factor (CHPF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chondroitin Polymerizing Factor (CHPF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chondroitin Polymerizing Factor (CHPF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chondroitin Polymerizing Factor (CHPF) ELISA Kit Customized Service Offer
  1. "Molecular cloning of a chondroitin polymerizing factor that cooperates with chondroitin synthase for chondroitin polymerization."J. Biol. Chem. 278:23666-23671(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Chondroitin sulfate synthase-2. Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities."J. Biol. Chem. 278:30235-30247(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  8. "Parkin interacts with Klokin1 for mitochondrial import and maintenance of membrane potential."Hum. Mol. Genet. 21:991-1003(2012) [PubMed] [Europe PMC] [Abstract]