Claudin 11 (CLDN11)

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OSP; OTM; Oligodendrocyte Transmembrane Protein

Claudin 11 (CLDN11)
Claudin-11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.Its nucleotide sequence shares little homology with previously reported genes, but the predicted amino acid sequence and structure of the gene product suggest that the protein, which they symbolized Osp, is the central nervous system (CNS) homolog of peripheral myelin protein-22.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF299Hu01 Recombinant Claudin 11 (CLDN11) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF299Hu01 Polyclonal Antibody to Claudin 11 (CLDN11) WB; IHC; ICC; IP.
MAF299Hu21 Monoclonal Antibody to Claudin 11 (CLDN11) WB; IHC; ICC; IP.
Assay Kits SEF299Hu ELISA Kit for Claudin 11 (CLDN11) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Claudin 11 (CLDN11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Claudin 11 (CLDN11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Claudin 11 (CLDN11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Claudin 11 (CLDN11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Claudin 11 (CLDN11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Claudin 11 (CLDN11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Claudin 11 (CLDN11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Claudin 11 (CLDN11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Claudin 11 (CLDN11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Claudin 11 (CLDN11) ELISA Kit Customized Service Offer
  1. "Involvement of OSP/claudin-11 in oligodendrocyte membrane interactions: role in biology and disease."J. Neurosci. Res. 59:706-711(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]