Cysteine And Glycine Rich Protein 2 (CSRP2)

CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3.

The deduced 193-amino acid protein, which the authors called CRP2, is 96%, 79%, and 66% identical to the quail CSRP2, human CSRP1, and human CSRP3 proteins, respectively. Northern blot analysis of human skin fibroblast RNA detected an approximately 1.0-kb CSRP2 transcript.