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Cysteine And Glycine Rich Protein 3 (CSRP3)

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CLP; CRP3; MLP; CMD1M; LMO4; Cardiac LIM Protein; Cysteine-rich protein 3; LIM domain protein, cardiac; Muscle LIM protein

Cysteine And Glycine Rich Protein 3 (CSRP3)
CCC F337
HGNC 2472
MGI 1330824
PubMed 18505755
RGD 71092
UniProt P50461
Wiki CSRP3
CSRP3 encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans.
The rat cDNA was designated muscle LIM protein (Mlp) because it contains a cysteine-rich domain originally described in the 3 proteins Lin-11, Isl-1, and Mec-3. Mlp is enriched in striated muscle and its expression coincides with myogenic differentiation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cysteine And Glycine Rich Protein 3 (CSRP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cysteine And Glycine Rich Protein 3 (CSRP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cysteine And Glycine Rich Protein 3 (CSRP3) Polyclonal Antibody Customized Service Offer
Assay Kits SEF337Hu ELISA Kit for Cysteine And Glycine Rich Protein 3 (CSRP3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cysteine And Glycine Rich Protein 3 (CSRP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cysteine And Glycine Rich Protein 3 (CSRP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cysteine And Glycine Rich Protein 3 (CSRP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cysteine And Glycine Rich Protein 3 (CSRP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cysteine And Glycine Rich Protein 3 (CSRP3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cysteine And Glycine Rich Protein 3 (CSRP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cysteine And Glycine Rich Protein 3 (CSRP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cysteine And Glycine Rich Protein 3 (CSRP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cysteine And Glycine Rich Protein 3 (CSRP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cysteine And Glycine Rich Protein 3 (CSRP3) ELISA Kit Customized Service Offer
  1. "Mapping of a human LIM protein (CLP) to human chromosome 11p15.1 by fluorescence in situ hybridization."Genomics 28:602-603(1995) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Structure and dynamics of the human muscle LIM protein."FEBS Lett. 583:1017-1022(2009) [PubMed] [Europe PMC] [Abstract]
  4. "The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy." Cell 111:943-955(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy."Circulation 107:1390-1395(2003) [PubMed] [Europe PMC] [Abstract]
  6. "Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy." Hum. Mol. Genet. 17:2753-2765(2008) [PubMed] [Europe PMC] [Abstract]